The Quebrada del Profeta, also known as Quebrada del Monigote, is an intermittent watercourse located in the Antofagasta Region of Chile. It originates on the western slopes of the Cordillera de Domeyko, approximately 200 kilometers southeast of the city of Antofagasta. The waterway is part of an intramontane basin and has a recorded length of 221 kilometers. As an intermittent stream, its flow is not constant and is highly dependent on seasonal rainfall patterns, which is the primary consideration for any paddling activity. The region is arid, and the channel is likely dry for significant portions of the year, with water present primarily during and after rare precipitation events in the mountains. This defines the overall character of the experience, which would be one of navigating a desert wash through a geologically significant basin rather than a traditional river trip. The landscape is defined by the Cordillera de Domeyko, suggesting dramatic, barren mountain scenery. Specific access points, hazards, regulations, amenities, water quality, temperature, or recommended routes for paddlers are not available. The intermittent nature of the flow means planning a trip would require extensive local knowledge of recent weather conditions in the headwaters, and self-sufficiency is essential due to the remote desert environment.