Laguna Grande in Argentina is referenced in two distinct geographical contexts, both of which are relevant to paddlers. The first is located in the province of Entre Ríos, where it forms part of a named paddling route. The Paraná - Victoria vía Paraná River and Laguna Grande Paddling Route is a designated trail where paddle sports such as canoeing, kayaking, and paddleboarding are explicitly permitted. This suggests the water body is integrated into a riverine system suitable for recreational paddling.

The second Laguna Grande is a significant wetland located in the north of Catamarca province, within the Antofagasta de la Sierra department. This high-altitude environment is part of a route that begins from a village at approximately 3,400 meters of elevation and leads to Laguna Diamante at around 4,200 meters, with the highest point on the route reaching 4,000 meters. The primary season for visiting this area is between October and March. Paddlers considering this location should be aware of the extreme altitude, which presents significant physiological challenges, and the remote, high-desert environment. The seasonality indicates access is likely limited to the warmer months, outside of the Southern Hemisphere winter.