The Rio Coxipó-Açú is a river located in the state of Mato Grosso, Brazil. It originates in the municipality of Chapada dos Guimarães, descending from the Serra de Guimarães. The river's basin has been the subject of environmental vulnerability studies, indicating a natural landscape that may be sensitive to changes. One recorded paddling trip involved a visit to the Coxipó-Açú community for the purpose of exploring the river and conducting an initial assessment for potential paddling routes, suggesting the river is used for recreational paddling, at least on an exploratory basis. The character of the paddling experience is likely influenced by its origins in the highlands of Chapada dos Guimarães, which could imply sections with varying flow. Specific details regarding definitive access points, hazards, seasonal water levels, water temperatures, regulations, or established routes are not detailed. The trip to the community indicates that human settlements exist along its course, but no specific facilities or amenities for paddlers are mentioned. The river's course through the Mato Grosso landscape likely offers views of the regional flora and fauna, though no specific wildlife features are enumerated.