The Kaaimans River is located near Wilderness on the Garden Route in the Western Cape, flowing through a narrow sandstone gorge before meeting the sea. The river mouth sits directly below the N2 highway bridge, approximately 15 minutes by car from George Airport. The standard put-in is at the beach car park just off the N2, reached by turning left immediately after crossing the Kaaimans River bridge when heading west from Wilderness toward George. Coordinates for the car park are approximately 33.998° S, 22.571° E.

The river offers two distinct paddling experiences. The estuary and gorge section is tidal in its lower reaches, keeping currents gentle and the water calm enough for complete beginners. Paddling upstream from the river mouth, the gorge closes in within roughly ten minutes, with sandstone walls draped in vegetation rising on both sides and a forest canopy overhead. The route continues to a small waterfall, with the full trip taking around one hour. A giant Yellowwood tree provides a notable landmark and picnic spot along the way. The iconic curved railway bridge, the first of its kind built in South Africa (1952), is visible near the river mouth and is a frequently cited highlight of the paddle.

For whitewater paddlers, the upper sections of the Kaaimans offer more technical water rated Grade 2–5 depending on conditions and water levels. The upper section runs from a pump station below Saasveld to the 7 Passes bridge and is described as an easy paddle with one spot that often requires portaging on the right due to strainers. Water levels significantly affect the grade, and paddlers should be aware that tree blockages occur from time to time in narrower channels.

Kayak and stand-up paddleboard rentals are available at the beach car park during peak season, which runs from October to April. This period also offers warm water and long days. The May to August winter months are quieter, with cleaner water and favorable morning light in the gorge. Paddlers may bring their own craft year-round. Boat surf-launching through the river mouth is practiced by local fishing clubs but is only possible during certain tidal windows and when the estuary is open, which is limited to a few months of the year.