The South Branch Kedgwick River is a tributary that flows through the Restigouche region of northern New Brunswick, joining the North Branch at a confluence known as Kedgwick Forks. The river rises in the Notre Dame Mountains area and drains through dense boreal forest dominated by spruce and fir. The combined Kedgwick River, formed at the forks, runs approximately 80.8 km southeast before meeting the Restigouche River.

The South Branch upstream of Camp 28 is considered more technically demanding, with Class 2 and Class 3 rapids in addition to general whitewater and Class 1 sections. This upper portion is recommended only for experienced canoeists and only when water levels are high. Below Camp 28 and from Kedgwick Forks onward, the character of the river becomes more accessible, with a steady current, numerous rips, and only moderate whitewater. The most notable feature on the main Kedgwick below the forks is a Class 2 to Class 2+ rock garden stretching roughly 500 metres.

A common multi-day route begins at Kedgwick Forks and continues downstream on the Kedgwick River to the Restigouche, covering roughly 150 km over approximately five days with no portages required. Nature Aventure offers guided four- and five-day trips on this corridor. The banks along the river are steep in places, particularly on the left-hand shore in certain sections, and at least one lookout platform is visible high above the river, accessible by a steep bushwhack involving a 120- to 150-metre elevation gain. A small campsite on river right, bisected by a brook, provides one overnight option along the route.

Logging roads run close to both banks along much of the Kedgwick corridor. Atlantic salmon fishing is a significant activity on the river, and paddlers should expect to encounter anglers, particularly fly fishers. The Kedgwick Salmon Club holds leased fishing sections on the river and enforces a strict live-release policy for all salmon and grilse. Paddlers sharing the water with anglers should be aware of this fishing culture and the associated regulations that govern the river.