The Spruce River in Saskatchewan originates in the Waskesiu Hills within Prince Albert National Park and flows generally southward through boreal forest, glacier-carved hills and valleys, muskeg, and prairie before emptying into the North Saskatchewan River at the eastern edge of the city of Prince Albert. The river is also known by the alternate name Little Red River.

The most commonly paddled section runs from a launch point near the junction of highway 263 downstream to Anglin Lake, a distance of approximately 25 kilometres or less. This stretch lies within or adjacent to Prince Albert National Park and passes through the Great Blue Heron Provincial Park area. The character of this section is flatwater and meandering, with tight bends through cattails and a valley setting. Paddlers should expect to encounter multiple beaver dams along the route that require pulling over or portaging. The river is rated suitable for novice paddlers, though a basic level of fitness and agility is helpful for managing the beaver dam crossings and getting in and out of canoes.

The take-out at Anglin Lake is facilitated by leaving a shuttle vehicle at the lake beforehand. Parks Canada lists the Spruce River as a short trip option within Prince Albert National Park, and the route can also be paddled in reverse from Anglin Lake upstream. Water levels can run low at times, which affects the experience but does not necessarily prevent paddling.

Anglin Lake itself is noted for having one of the higher densities of common loons in Saskatchewan, making the transition from river to lake a notable wildlife-watching opportunity. The river corridor also supports otters and other boreal wildlife. The scenery along the river includes tamarack trees, which take on colour in autumn, adding visual interest to fall paddling.

Facilities near the take-out at Anglin Lake include the Spruce River Campground within Great Blue Heron Provincial Park, which offers fire pits, an outdoor toilet, a log gazebo, and firewood. A boat launch and beach are also available in the provincial park area. Watercraft rentals are available within Prince Albert National Park through the Waskesiu Chamber of Commerce for those without their own equipment.