Lough Graney (Irish: Loch Gréine) is a freshwater lake in County Clare, in the east of that county. It covers approximately 3.7 square kilometres (about 919 acres) with a shoreline of roughly 8.37 miles, and sits at an elevation of 49 metres above sea level. The lake contains two islands, Green Island and Sand Island, which provide points of interest for paddlers exploring the water. The lake's coordinates place it at approximately 52°59'N, 8°40'W.

Water drains from Lough Graney via the River Graney, a short outflow that passes through Lough O'Grady and continues past the town of Scarriff before joining the western side of Lough Derg, itself part of the River Shannon system.

One documented paddling route runs from the hamlet of Caher northward along the lake to the Cahermurphy woodland area at the north end, with the Bleach River accessible at that end. This route covers approximately 12 kilometres out and back. The northern woodland area offers a landing point suitable for a break. Autumn conditions on the lake can produce flat calm water and, following cold nights with frost, cloud inversions over the surrounding landscape.

The lake is well known for fishing, with species including perch, ferox trout, roach, and bream present. Anglers and paddlers may share the water, which is worth bearing in mind when planning a route.

Lough Graney holds a notable place in Irish literary history. In 1780, local poet and hedge school master Brian Merriman set the opening of his mock-Aisling poem Cúirt An Mheán Oíche ("The Midnight Court") along the lake's shores. A carved stone bearing the opening lines of the poem in Munster Irish stands overlooking the site, making the shoreline of cultural as well as natural interest to visitors.