Owyhee Lake Road is a narrow, winding 22. 8-mile paved route built in the 1930s that provides the primary vehicle access to Owyhee Lake Reservoir in eastern Oregon's remote desert canyon.

The road features steep grades, unlit tunnels, no guardrails, and significant hazards including rockfall risk and mudslide potential during heavy storms, requiring cautious driving and high-clearance vehicles.

Access points include boat ramps at Indian Creek and Leslie Gulch, with campgrounds and facilities available at Lake Owyhee State Park.