The Río Queuco is a tributary of the Río Bío-Bío in the Biobío Region of Chile, joining the main river at an elevation of approximately 330 meters. The confluence with the Bío-Bío serves as a notable reference point for paddlers on both rivers, and a balsadero (river crossing point) is located somewhat above this confluence, providing a convenient access area.

The river has been documented as a paddling destination of roughly 25 km in length, with the character of the run involving navigation through boulder fields. The late paddler and guidebook writer John Foss explored and described the Queuco, and subsequent paddlers have completed shortened versions of his original route. The boulder-strewn nature of the river suggests technical paddling demands, though specific difficulty ratings are not well documented.

The Río Queuco holds considerable cultural significance for the Mapuche Pewenche communities of Alto Biobío, who have organized around the river's protection and conservation. Community organizations including "Por la defensa del río Queuco" have been active in advocating for the river, and paddling programs have been developed in the area to connect local youth with whitewater skills and river stewardship. Paddlers visiting the area should be aware of this cultural context and the importance of the river to local communities.

Given its location in the Biobío Region and its role as a tributary feeding into the lower Bío-Bío system, the Queuco is accessible from the road corridor that runs through the Alto Biobío valley. Paddlers planning a trip to the area often combine the Queuco with runs on the lower Bío-Bío, which puts in at the Queuco confluence.