Lago Grey sits within Torres del Paine National Park in the Magallanes and Chilean Antarctica Region, and is defined by its proximity to the Grey Glacier, whose calving ice wall feeds the lake with floating ice floes and icebergs of varying sizes. The lake's most striking visual feature is the constant presence of these blue-tinged ice masses drifting across its surface, set against the backdrop of the glacier's towering ice walls.

The primary access point for paddlers is Playa Grey, adjacent to Refugio Grey (also referred to as Grey Refuge or Grey Shelter). Reaching this sector requires either an overnight stay at Refugio Grey or Camping Grey, or arriving via the Lago Grey catamaran navigation service. This logistical requirement means paddlers cannot simply drive to the put-in; advance planning around accommodation or boat transfers is essential.

Guided kayak excursions operate as half-day outings, departing at multiple times including 08:00, 11:00, and 16:30. The route heads toward the east side of the Grey Glacier, paddling among floating ice floes and approaching the glacier's ice walls. Depending on conditions, the return route may pass by a small island feature called Nunatak. The physical demand is rated as medium, and the activity is considered accessible to beginners, though a basic level of fitness is recommended.

Weather on Lago Grey is highly variable and can change rapidly within a single day, shifting between strong gusts, cold temperatures, and sunshine. All activities are subject to cancellation or route modification based on weather and lake safety conditions. Paddlers are advised to bring a hat, gloves, a windproof jacket, sunglasses, sunscreen, and spare clothing. Guided operations provide neoprene suits, waterproof jackets and boots, kayak gloves, spray skirts, and lifejackets.

Entry to Torres del Paine National Park requires a paid entrance fee, which is not included in kayak tour pricing. The park fee is payable separately and in advance or at the destination. Paddlers should also note that cash is advisable, as banking facilities are limited in the region; ATMs are available in Punta Arenas and Puerto Natales but not within the park itself.