The Río Paraná in Misiones, Argentina offers paddlers a river experience set against the backdrop of the Paranaense Jungle, one of the largest remaining continuous blocks of Atlantic Forest in the world. The province of Misiones holds roughly 1,128,343 hectares of this forest, and the river corridor reflects that biodiversity directly from the water.

Guided kayak tours operate out of several points along the river. Puerto Bemberg is a well-established launch site where instructors meet paddlers at the embarcadero for two-hour excursions. From there, routes head toward the mouth of the Arroyo Urugua-í, with views across to the Paraguayan bank. The activity is rated low difficulty and is suitable for beginners, though children under six years of age are not permitted. Departures are subject to weather conditions. Paddlers are advised to bring identification documents, insect repellent, sunscreen, closed-toe shoes, long pants, and a swimsuit.

In Montecarlo, guided kayak tours circumnavigate Isla Caraguatay, a 32-hectare island in the Paraná. This route takes approximately three hours and includes a stop on the island's sand beach. No prior kayaking experience is required, and tours include kayaks, paddles, life jackets, and safety equipment. A registered professional guide accompanies all groups, and advance reservations are required.

Wildlife visible from the water includes howler monkeys, eagles, parakeets, parrots, and toucans. Notable tree species along the banks include the black lapacho, which can reach 30 meters in height, and the Paraná pine, the largest tree in the Paranaense Jungle at up to 40 meters tall. The palo rosa, a protected species, is also present in this ecosystem.

Hotel Puerto Valle, located along the river, also offers guided kayak tours as part of its activities, framing the experience as suitable for nature observation and photography. The river's character in this stretch is defined by its wide channel, forested banks, and proximity to the international border with Paraguay.