The Otheense Kreek is a creek system in Zeeuws-Vlaanderen, with its mouth on the east side of Terneuzen. About a kilometer inland it splits into two tributaries — a southern branch toward Axel and an eastern branch running through Zaamslag.

Much of the creek remains water-filled and navigable for several kilometers inland. The creek is a popular recreational destination owned by the municipality of Terneuzen.

It supports swimming, sailing, surfing, rowing, canoeing, and both bank and boat fishing. Around 50 dedicated fishing spots line the banks, with fishing permits issued by angling association ONI.

A marina, several boat jetties, and boat ramps serve water users, and the "Rondje Kreek" walking route circles the waterway and includes a small beach. Anglers commonly catch Northern pike, European perch, tench, and round goby here.