The Whitewater River originates in eastern Indiana and flows southeast, eventually crossing into Ohio before joining the Great Miami River. Its main stem forms at the confluence of its West and East Forks near Brookville, Indiana. The river's watershed encompasses parts of nine counties across Indiana and Ohio.

Paddlers can enjoy a variety of experiences on the Whitewater, from calm flatwater stretches to occasional Class II rapids. The most popular sections for canoeing and kayaking are found between Laurel and Brookville in Indiana. A 7-mile trip from Laurel to Metamora offers an easy 3-hour float suitable for beginners, while more ambitious paddlers can continue an additional 10 miles to Brookville for a full-day adventure.

The river's character changes seasonally, with spring typically bringing higher water levels that increase both flow and difficulty. Summer and early fall provide more relaxed conditions ideal for family outings and fishing trips. The Whitewater is generally rated Class I-II, though some tributary creeks like Elkhorn Creek can reach Class III-IV during high water.

Sycamores and silver maples line much of the riverbank, providing habitat for great blue herons, bald eagles, and various waterfowl. Smallmouth bass and rock bass are abundant, making the Whitewater a popular destination for anglers.

Key landmarks include the historic Metamora Aqueduct, part of the Whitewater Canal State Historic Site, and Brookville Lake, formed by damming the East Fork. The river played a significant role in early Indiana's development, powering mills and facilitating trade via the Whitewater Canal in the 19th century.

Primary access points are found in Laurel, Metamora, and Brookville, Indiana, as well as near Harrison, Ohio. Several outfitters offer rentals and shuttle services, with Morgan's Canoe Rental in Brookville being a popular choice.

While mostly gentle, the Whitewater can pose hazards during high water or after storms. Paddlers should be aware of potential strainers and check water levels before their trip. A fishing license is required for anglers in both states.

For those seeking a multi-day experience, primitive camping is available at designated sites along the river, allowing for extended trips of up to 34 miles from Metamora, Indiana to Elizabethtown, Ohio. This longer journey showcases the river's transition from Indiana's rolling hills to Ohio's flatter terrain.