The Sable River in Nova Scotia flows through Shelburne County in the southwestern part of the province, emptying toward the Atlantic coast. The primary access point for paddlers is at Sable River Bridge on Highway 103, where a private landowner has granted permission to use the site as a put-in. Paddlers should respect private property at all times when using this access. The shoreline at the bridge is rocky and gravelly. Vehicles can be driven down into the field just above the bridge, and parking is also available at the carpool area near the Lockeport exit 23 off Highway 103.

The recommended route runs from Sable River Bridge downstream to Louis Head Beach, described as an interesting and scenic paddle. Paddlers can arrange a vehicle shuttle to be picked up at the beach, or plan an overnight trip using the Louis Head Beach Campground, which has a small canteen and other amenities. A critical tidal consideration applies to this route: paddling is described as impossible at low tide, so checking tide tables before launching is essential for trip planning.

The topographic reference for the area is map 20 P/14 (Shelburne), and the relevant marine chart is 4240 (Liverpool–Lockeport). The UTM grid reference for the Sable River Bridge access is E0333905 N4856097, at approximately 43° 50.464′ N, 65° 03.991′ W.

Near the access point, the Sable River Walking Trail offers additional exploration on foot. The trail includes a pedestrian suspension footbridge — noted as the only one of its kind in the area — and connects to the Tom Tigney Trail in a route locally referred to as "going around the River." Two garages near the Sable River Bridge on Highway 103 carry snacks and hot and cold drinks. A provincial park picnic area is located just off Highway 103 at Lockeport exit 23, providing an additional nearby facility for paddlers.