Keefer Cutoff is a specific, named channel of the lower Nushagak River in Alaska, branching off from the main river just below Koggiling Creek. It is the eastern of two main channels and runs for approximately 15 miles before rejoining the main Nushagak River. This section is part of the river's lower tidal zone, where paddlers will encounter mudflats and significant tidal influences. The primary access point for paddlers is a boat launch adjacent to the Keefer Cutoff, which is located north of Portage Creek. This launch area is identified as a shoreland site used for camping and angling. The broader region from the Keefer Cutoff downstream to the Wood River is managed as a specific recreational unit, indicating established use. Paddlers should be prepared for motorboat traffic, especially as they approach Dillingham, and should be aware that floatplanes commonly land at many spots along the river. The area is remote, with Dillingham being the major hub for commercial flights and services. A notable hazard is the boat launch itself, which has been identified as having the highest risk in its vicinity. The overall character is that of a wide, braided tidal river in a vast, undeveloped landscape.