Lago Krügger is located within Los Alerces National Park in Chubut, Argentina, a protected area and UNESCO World Heritage Site that borders Chile to the west. The lake sits in a remote section of the park and is surrounded by wilderness, with larch and cypress forests characteristic of the broader park landscape.

Access to Lago Krügger is not straightforward. The primary overland route begins at Puerto Chucao and involves a 28 km trek that typically takes two to three days one-way, making it a multi-day backcountry commitment. Boat access can also be arranged through the park. At the north end of the lake, Puerto Patriada offers a rustic refugio with bunks and meals for backpackers, though advance arrangement is required. Backcountry camping registration is mandatory for anyone venturing into this area, and paddlers should be prepared with navigation skills, as the trail and surroundings are remote even if marked.

Kayaking on the lake is an established activity, and Lago Krügger also draws fly fishing interest, with guides targeting rainbow trout, brown trout, and brook trout in its waters. Paddlers should be aware that afternoon winds on the lakes within Los Alerces National Park can be strong, a factor worth accounting for when planning daily schedules on the water.

The best season for paddling is December through February, the Southern Hemisphere summer, when daytime temperatures range from 15 to 25°C, nights from 5 to 10°C, and daylight extends roughly from 6 AM to 10 PM. All park facilities are open during this period. Given the lake's remote location and the logistics involved in reaching it, trip planning well in advance is advisable, including coordinating boat transport and registering backcountry camping with park rangers.