Okatibbee Creek is a scenic waterway in east-central Mississippi, originating in Kemper County and flowing southward to join the Chunky River, forming the headwaters of the Chickasawhay River. This creek system is part of the larger Pascagoula River Basin. The creek's most notable feature is Okatibbee Lake, a 3,500-acre impoundment created in 1968 to reduce flooding along Okatibbee Creek and the Chickasawhay River.

Paddling opportunities on Okatibbee Creek range from flatwater lake paddling on Okatibbee Lake to more adventurous creek paddling on the upper and lower sections. The lake offers over 4,000 acres of surface area, with four boat ramps providing easy access for kayaks and canoes. Paddlers can explore the lake's numerous coves and inlets, as well as the Okatibbee Wildlife Management Area on the north side, partially accessible by water.

The difficulty of paddling Okatibbee Creek varies from easy flatwater on the lake to more challenging sections on the flowing creek. Upper Okatibbee Creek, above the lake, offers a mix of flatwater and mild rapids, suitable for beginner to intermediate paddlers. The creek is characterized by rocky shoals and cypress-lined banks, providing an intimate paddling experience.

Spring and fall are ideal times for paddling Okatibbee Creek, offering comfortable temperatures and typically stable water levels. Summer paddling is popular for fishing and cooling off, though afternoon thunderstorms can be a concern.

The creek's ecosystem supports a diverse array of flora and fauna. Cypress trees and their distinctive knees line the banks, creating excellent habitat for wildlife. The waterway is known for its prolific red-eye bass population, making it a favorite among anglers. Other fish species include spotted bass, crappie, and catfish.

Key landmarks include Okatibbee Lake, with its full-service campground, day-use parks, and marina. The lake's dam is a significant feature, marking the transition between the upper creek and the impoundment. Access points for paddling include the four boat ramps on Okatibbee Lake, though specific put-in and take-out locations for creek sections are less well-documented. The nearby town of Collinsville serves as a gateway to the Okatibbee Lake area.

Historically, the creation of Okatibbee Lake significantly altered the creek's ecosystem and surrounding landscape. Today, the creek and lake play important roles in flood control, recreation, and wildlife conservation for the region.

Safety considerations include being aware of weather conditions, especially on the open waters of Okatibbee Lake where wind can create challenging conditions for paddlers. Wearing a life jacket is essential, and paddlers should be cautious of submerged obstacles in the creek sections. While multi-day trips are not commonly advertised, the combination of creek paddling and lake exploration could potentially be extended into an overnight adventure for well-prepared paddlers, utilizing the campground facilities at Okatibbee Lake.